Health Benefits of Bitter Gourd

Bitter gourd is a popular vegetable in some Asian countries, where the health benefits of the plant are well-known—particularly, its ability to lower blood glucose in diabetics. Bitter gourd has been used to treat diabetes in traditional medicine and is now commercially available as tea (from fruits or leaves), juice, extracts, and pills. Although these products promise health benefits, most of the manufacturers do not offer scientifically proven data on the effectiveness of bitter gourd or their products. However, in recent years researchers worldwide have started to focus on the antidiabetic effects of bitter gourd. The goal is to provide safe and clear preparation and dosage recommendations so that consumers will realize the greatest benefit from consuming fresh bitter gourd or bitter gourd products.

Bitter gourd (melon) is the secret of the Okinawa Islander longevity! Although, the bitterness of this gourd might turn some people away from it, in-fact, it can really sweeten your health because of its disease preventing and health promoting phyto chemical compounds.

Bitter gourd treatments of cell cultures or feeding trials with laboratory animals such as mice or rats show bitter gourd does have blood glucose lowering properties. Bitter gourd is not like most medicinal drugs, which are effective only in one target organ or tissue; rather, it influences glucose metabolism all over the body.

The glucose metabolism starts in the gut. Carbohydrates and sugars are metabolized to glucose (one type of sugar) before glucose is transported from the gut to the blood. Bitter gourd reduces the amount of glucose that is released into the blood by inhibiting the enzymes that break down disaccharides to two monosaccharides (e.g. glucose) (Oishi et al. 2007, Kumar Shetty et al. 2005). Bitter gourd can influence the transport channels for glucose, which also reduces glucose transport into the blood (Singh et al. 2004). This effect is important for the treatment of both Type I and Type II diabetic patients and helps to prevent high blood sugar levels after meals.

The pancreas reacts to increasing blood sugar levels by secreting insulin into the blood. Insulin helps to transport the sugar from the blood to the skeletal muscle and the fat tissue where it is used to produce energy. Insulin will also stop the liver to produce sugar from glycogen storages and to release the sugar into the blood.

Thus, insulin is necessary to lower high blood sugar levels. In Type I diabetes, also called insulin-dependent diabetes, the pancreas does not produce or secrete enough insulin to keep blood sugar levels low. Bitter gourd has been shown to be effective in treating Type I diabetes in rats or mice by increasing pancreatic insulin secretion Yibchok-Anun et al. 2006, Fernandes et al. 2007). Additionally, scientists found an insulin-like molecule in bitter gourd (Khanna et al. 1981). Although bitter gourd may reduce the number of insulin injections required to manage Type 1 diabetes, it cannot replace insulin treatment completely or heal this form of the disease.

• Bitter melon notably contains phyto-nutrient, polypeptide-P; a plant insulin known to lower blood sugar levels. In addition, it composes hypoglycemic agent called charantin. Charantin increases glucose uptake and glycogen synthesis in the cells of liver, muscle and adipose tissue. Together, these compounds are thought to be responsible for reduction of blood sugar levels in the treatment of type-2 diabetes.
  
  
  
  
  
• Fresh pods are an excellent source of folates, contain about 72 µg/100g (Provides 18% of RDA). Folate helps reduce the incidence of neural tube defects in the newborns when taken by mothers during early pregnancy.
  
  
• Fresh bitter melon is an excellent source of vitamin-C (100 g of raw pod provides 84 mg or about 140% of RDI). Vitamin-C, one of the powerful natural antioxidants, helps the body scavenge deleterious free radicals one of the reasons for cancer development.
  
  
• It is an excellent source of health benefiting flavonoids such as ß-carotene, α-carotene, lutein, and zea-xanthin. It also contains a good amount of vitamin A. Together; these compounds help act as protective scavengers against oxygen-derived free radicals and reactive oxygen species (ROS) that play a role in aging, cancers and various disease processes.
  
  
• Bitter melon stimulates easy digestion and peristalsis of food through the bowel until it is excreted from the body. Thus, helps in relieving indigestion and constipation problems.
  
  
• In addition, the vegetable is an also good source of niacin (vitamin B-3), pantothenic acid (vitamin B-5), pyridoxine (vitamin B-6) and minerals such as iron, zinc, potassium, manganese and magnesium.
  
  
  Exclusive consumption of bitter gourd, bitter gourd juice, or other bitter gourd products can lead to dangerous hypoglycemia when consumed by diabetic patients under oral drug treatment, in too high dosages, by children, or on a hungry stomach. Pregnant or breastfeeding woman should not consume bitter gourd or bitter gourd products. Although bitter gourd can help prevent insulin resistance or severe diabetic complications, it is important to consider situations in which bitter gourd may be harmful to your health.